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Not intended for U.S. and UK media - Molecular Imaging:
Berlin, April 15, 2012 - Bayer has entered into an agreement to sell its PET
tracer assets envisioned to be used as in-vivo diagnostic agents, including its
PET compound florbetaben, to Piramal Imaging SA. Florbetaben is a late-stage
investigational PET tracer currently in development for the detection of ?-
amyloid plaques in the brain. These ?-amyloid plaques are one of two
pathological hallmarks of Alzheimer's dementia, the most common form of
dementia. A Phase III study, aimed at providing histopathological verification
that florbetaben can reliably detect ?-amyloid, has been completed. The results
of this trial with florbetaben will be presented to the scientific community
for the first time at the American Academy of Neurology Annual Meeting in New
Orleans in April 2012.
"This transaction provides a clear strategic benefit for Piramal and Bayer,"
said Roland Turck, Head of Specialty Medicine at Bayer HealthCare
Pharmaceuticals. "For Bayer, the transaction enables us to free up resources to
concentrate and accelerate the development of our exciting late stage pipeline.
And Piramal will be better able to leverage the existing clinical, regulatory
and marketing investments in florbetaben".
Piramal will acquire the intellectual property rights relating to Bayer's PET
tracer assets and will apply for marketing authorizations covering Bayer's PET
tracer compound florbetaben. Closing of the transaction is expected in the
second quarter of 2012. Bayer will continue to provide certain services for the
development of florbetaben.
The parties have agreed on certain milestone and royalty payments.
About Florbetaben (BAY 94-9172)
Florbetaben is an F-18-labeled PET tracer that is currently being investigated
for imaging of cerebral beta-Amyloid plaques. As the aggregation of the
beta-Amyloid protein in the brain is a key target for new therapeutic
treatments under development for Alzheimer's disease, florbetaben might also be
able to support the development of these new treatment approaches.
About the Piramal Group
The Piramal Group, led by Ajay G. Piramal is one of India's foremost business
conglomerates. Driven by the core values of Knowledge, Action and Care, the
Piramal Group has interests in a myriad of industries that encompass
healthcare, drug discovery & research, diagnostics, glass, real estate and
financial services. The Piramal Group steadfastly pursues inclusive growth
while adhering to ethical and value driven practices. The Group's turnover
exceeded $ 900million in FY2011.
About Piramal Healthcare Ltd.
Piramal Healthcare is one of India's largest healthcare companies, with a
growth track record of above 29% CAGR since 1988. Piramal Healthcare had
consolidated revenues of $ 650 million in FY2011. With assets across North
America, Europe and Asia, Piramal Healthcare is also one of the largest custom
manufacturing companies across the world. It has significant presence in the
global critical care space with sales of anesthesia products to over 100
countries. In 2010, Piramal Healthcare sold its domestic formulation business
to Abbott for a consideration of US $ 3.8 billion.
About Bayer HealthCare
The Bayer Group is a global enterprise with core competencies in the fields of
health care, nutrition and high-tech materials. Bayer HealthCare, a subgroup of
Bayer AG with annual sales of EUR 17.2 billion (2011), is one of the world's
leading, innovative companies in the healthcare and medical products industry
and is based in Leverkusen, Germany. The company combines the global activities
of the Animal Health, Consumer Care, Medical Care and Pharmaceuticals
divisions. Bayer HealthCare's aim is to discover, develop, manufacture and
market products that will improve human and animal health worldwide. Bayer
HealthCare has a global workforce of 55,700 employees (Dec 31, 2011) and is
represented in more than 100 countries. Find more information at
www.bayerhealthcare.com.
Find more information at www.bayerpharma.com.
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